About Us

Alto Predict helps biomedical researchers find and use human cell-based alternatives to animals to advance human-relevant science for better decisions in drug discovery and product development.

We work with assay developers, biomedical researchers, regulators, industry consortia and startups to advance the development and application of these technologies for better, safer products. These alternatives, known as in vitro NAMs or novel alternative methods, range from simple 2-dimensional cell cultures to organoid-based and microphysiological systems (MPS) or organs-on-a-chip.

Alto Predict is creating data products to support easier access to and understanding of these technologies: a catalog of commercially available human in vitro NAMs and a knowledge base to guide the use of reference control compounds in assay qualification.

We are also building a discovery engine using proprietary relational ontologies applied to in vitro data sets from diverse, human-based assays and platforms to support program decisions, predict drug effects, and discover target functions.

Leadership

Ellen Berg is a scientific leader specializing in human cell-based in vitro assays and platforms for drug discovery and chemical safety applications. Her expertise is in assay development, mechanisms of drug and disease biology, and research data management.

Dr. Berg has a background in biopharmaceutical research and drug discovery contract research services with startup, operations, and commercialization experience. Ellen led the development of BioSeek’s BioMAP® human primary cell-based profiling platform, now a commercial service of Eurofins Discovery.

Her research interests include mechanisms of human disease biology and drug action, predictive toxicology, and research information science, (including AI/ML approaches and data visualization) and she is working to promote FAIR data (Findable, Accessible, Interoperable and Reusable data) and the use of human-based alternatives to animals, or NAMs (Novel Alternative Methods), in biomedical research and product development.

Connect with Ellen on LinkedIn.